The owner of one of the best (perhaps the best) health food stores where I live is a minimalist for that very reason...
He knows that my nutritional focus is on the highest quality foods, herbs and spices I can get my hands on... and during one of our discussions, he shared his views with me.
None, to minimal (depending upon food sources) supplements if any at all... the rest... the very best foods, reasonable amounts of water, sun, exercise, work, rest/sleep, etc.