Hi, Burt's Bees Diaper Cream has Zinc Oxide in it. ZZ cream has zinc oxide in it so I am thinking it will work as well as ZZ on Demodex. Whenever a skin issue arises I whip out the Burt's Bees Diaper Cream. It takes care of everything from fungus to diaper rash to pimples, and I am thinking it would work for Demodex and rosacea. It dries everything out and takes away pain and infection. I would put it under my babies mouth when he was in the drooling stage and it would take care of the pimply rash that he had from all the moisture. It has such soothing ingredients and is available in stores as opposed to having to order it on the internet. It is awesome and a non-toxic remedy. Also if you mix it with lotion or oil it is a great sunblock.