I thought maybe that on the long run the therapy would regulate the pineal gland (located in the brain) which is responsible for the secretion of melantonin...
I am not afraid at all to poke. I would imagine you could also scratch (after a few hours of immersing in urine). That is what happened to me as I realized it was peeling starting to peel. I scratch almost a quarter of the mole out before I read about the poking. Urine is an antiseptic so I am not afraid for infection. You don't feel a thing.