I was one of the women who experienced irritation/infections with the Mirena. They started within 1 week of getting it. I had the device for 11 months before having it removed in 2/07. The itching and irritation still occured off and on. I finally went to a new dr and he said I have Lichen Simplex. You get it from the constant itching from irritants. He said its most likely from the Mirena since the itching starting after insertion. I always wear cotton underwear and used sensitive soaps and free & clear detergents. My old dr didnt get it ! He blamed everything but that stupid device.