Probiotics can be kept non-refrigerated for a few days without suffering too much damage.

JV.

Probiotics that require refridgeration should be fine for several days out of the fridge. My understanding of Candida is that it has a tough protein shell. My daughter has had success with using a probiotic that acts on protein (proteolitic) , called Lactobasilus Salivarius. She has had a marked improvement

She has also just started to incorporate a protease enzyme formula that she uses when eating and on an empty stomach so that the enzymes get absorbed into the blood.

Both products were recommended by her Naturopathic doctor.

In general I completely agree with JV about probiotics, including refrigerated probiotics, doing OK without cooling for several days. My Metagenics probiotic I once used mentions on the label that no refrigeration for up to a week will not affect activity. But where I live (Southern California), summer temperatures above 100F are not uncommon. I've concluded that shipment of refrigerated probiotics during such times of the year simply won't guarantee a viable probiotic by the time it's delivered. In Fall, Winter, and early Spring, no problem. But a few days transit in a UPS/FedEx truck in August might be akin to baking a probiotic in a very low temp oven. For now I'm sticking to store-bought refrigerated probiotics, at least during the hot months. The same would apply if the probiotics ORIGINATE from a hot climate, so a shipment from Los Angeles could be affected even if it's being delivered to Alaska.