I heartily agree with the above comment. The liver needs to be flushed out in order for the milk thistle to work well. It shouldn't be used before it IS flushed out. Being able to pick out the truth from error is mostly a matter of getting yourself educated on the subject. Otherwise, a person can get mixed up and not know what to believe. I had to flush out my liver and then the milk thistle was of use to me. A sick liver really can't get protected if it can't heal with the bugs and stones in it. It can't heal until the garbage is gone, THEN the silymarin or milk thistle will work. Bring the body back to where the cells can get healthy by following the order of cleansing: colon, liver, blood, lymph and cells, then any good supplement that is natural will work. I learned this from experience. Clean out the colon and liver and the rest will clean out by itself. THEN and only then can all the good nutrients be used to the best advantage. Thats' why they tell you that the nutrients will work better for some than for others. It all depends on how clean your liver and colon is which dictates how clean the rest of the body is and how well the nutrients will work. Once the liver and colon are cleaned out, the rest follows automatically resulting in a major body clean-out once the 2 major plumbing organs are opened up. It works to get rid of any disease in the body. Been there and done it.