In another post you wrote that you have no fordyce spots. Do you have raw skin on your upper or lower lip? The acidophilus on lips is really meant for the raw skin. The good bacteria and dryness from acidophilus liquid cause the raw skin to scab and heal. You should only apply it on raw area of lip. The good bacteria seems to spread to rest of lip. Perhaps you applied too much?
I really cannot say how the results will be if you apply it overnight because I only applied it in the morning. Also, were you the one who applied vaseline over it at night?