Chagas disease (Trypanosoma cruzi) aka American trypanosomiasis

Date:   1/28/2010 4:05:18 PM ( 14 y ago)

NOTE:      To get quick relieve from a flare up run Active first, else skip and run only biofilm

program c  pulse 0 0  backfreq b 0 0
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# Title: Chagas disease (Trypanosoma cruzi) aka American trypanosomiasis - Spores are weaponized 
# Description: fever, malaise, and generalized swelling of one eye/lymph nodes. The liver and spleen may become enlarged,
#       Abnormal heart rhythms (arrhythmias, ventricular tachycardia) may cause sudden death.
#       Cerebral tumour, brain lesion and cerebrospinal fluid
# NOTE:      To get quick relieve from a flare up run Active first, else skip and run only biofilm
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label 0

label Active  # May be skipped, if no flare up exists, biofilm will hit them
dwell 300
duty 50
53763.8956      # Trypomastigote Mitochondrial
11000.1187      # Amastigote Mitochondrial - Stage I
dwell 180
17777.7856       # Amastigote Mitochondrial - Stage II
 6576.3757      # Spores, weaponized

label 1

label Biofilm
dwell 600
duty 82.4
vpulse 1 .01 82.4
657755.5578     # Nucleic Acid, all stages + biofilm

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# The acute phase, with high parasitaemia, commonly lasts around two months. Most of the cases are a- or oligosymptomatic, but depending on the
# inoculation site, the first sign can be a skin chancre (chagoma) or unilateral purplish orbital oedema (Romaña sign) with local lymphoadenopathies
# and fever over several weeks. That can be accompanied, among others, by headache, pallor, myalgia, dyspnoea, oedema in inferior limbs or face,
# abdominal pain, cough, hepatomegaly, rash, painful nodules, splenomegaly, generalized oedema, diarrhoea, multiple lymphoadenopathies, myocarditis
# (chest pain, heart failure) and more rarely meningoencephalitis (seizures, paralysis). Morbidity can be higher in children under five, elderly,
# immunocompromised or in cases with possible high parasite inoculum, such as seen in oral outbreaks. In AIDS the meningoencephalitis is the more
# frequent manifestation (differential diagnosis with toxoplasmosis).
#
# The chronic phase, with parasites hidden in target tissues - especially heart and digestive smooth muscle, has different possible clinical forms:
#   a) asymptomatic (indeterminate form), more frequent, typically in the beginning of the chronic phase and lasting all life in most of the patients;
#   b) cardiac form, till 30% of the patients, with conduction disorders, arrhythmia, cardiomyopathy, heart failure and secondary thromboembolism;
#   c) digestive lesions (megaoesophagus and megacolon) or mixed forms (cardiac plus digestive
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RifeFrqViaDowsing 

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